New study shows how regulating the degradation of messenger RNAs allows plants to grow organs properly

In an article recently published in the journal Nucleic Acids Research, author Rémy Merret of the LGDP laboratory at the University of Perpignan Via Domitia and the CNRS, and his colleagues, have succeeded in highlighting the importance of messenger RNA degradation in the model plant Arabidopsis thaliana, and more specifically in the proper development of its organs.

The degradation of messenger RNA (mRNA) is a process present in all living organisms and conserved throughout evolution. This mechanism is incredibly important for maintaining homeostasis within cells. This degradation process involves a number of different enzymatic processes which, until now, have remained largely unknown.

Using genetic and transcriptomic approaches, the team has succeeded in testing the importance of one of these degradation pathways in Arabidopsis leaves and roots. The fine characterization of this degradation process has shown that it is essential for maintaining general mRNA homeostasis and that it is indispensable for proper organ development. 

See also

Genome-wide analysis of mRNA decay in Arabidopsis shoot and root reveals the importance of co-translational mRNA decay in the general mRNA turnover. - M.C. Carpentier, A.E Receveur, A. Boubegtitene, A. Cadoudal, C. Bousquet-Antonelli, and R. Merret. - Nucleic Acids Research, 9 mai 2024. - https://doi.org/10.1093/nar/gkae363

Contact : Rémy Merret
remy.merret@univ-perp.fr