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DNA methylation landscapes Pacific Oyster Mortality Syndrome

DNA methylation landscapes before and after Pacific Oyster Mortality Syndrome are different within and between resistant and susceptible Magallana gigas

Researchers form IHPE, published in Science of Total Environment, their findings that enhance understanding of oyster-POMS interactions and highlight epigenetic biomarkers for disease management and oyster health

Pacific oysters are frequently affected by Pacific Oyster Mortality Syndrome (POMS), a polymicrobial disease influenced by environmental factors.

This study investigates the role of epigenetics, focusing on DNA methylation changes in resistant and susceptible oysters under basal and POMS-induced conditions. We identified differentially methylated regions (DMRs) in the gills and mantle, revealing distinct methylation patterns linked to immune response, metabolism, and transport. A set of 1998 epibiomarker candidates for resistance/susceptibility and 164 for POMS exposure was identified.

These findings enhance understanding of oyster-POMS interactions and highlight epigenetic biomarkers for disease management and oyster health

See also

DNA methylation landscapes before and after Pacific Oyster Mortality Syndrome are different within and between resistant and susceptible Magallana gigas
Valdivieso A, Morga B, Degremont L, Mege M, Courtay G, Dorant Y, Escoubas JM, Gawra J, de Lorgeril J, Mitta G, Cosseau C, Vidal-Dupiol J
Sci Total Environ . 2025 Jan 25:962:178385. doi: 10.1016/j.scitotenv.2025.178385. 
 

Modification date: 02 April 2025 | Publication date: 02 April 2025 | By: Tulip Communication